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Impact of COVID-19-related public containment measures on the ST elevation myocardial infarction epidemic in Belgium: a nationwide, serial, cross-sectional study.

Identifieur interne : 001A24 ( Main/Exploration ); précédent : 001A23; suivant : 001A25

Impact of COVID-19-related public containment measures on the ST elevation myocardial infarction epidemic in Belgium: a nationwide, serial, cross-sectional study.

Auteurs : Marc J. Claeys [Belgique] ; Jean-François Argacha [Belgique] ; Philippe Collart [Belgique] ; Marc Carlier [Belgique] ; Olivier Van Caenegem [Belgique] ; Peter R. Sinnaeve [Belgique] ; Walter Desmet [Belgique] ; Philippe Dubois [Belgique] ; Francis Stammen [Belgique] ; Sofie Gevaert [Belgique] ; Suzanne Pourbaix [Belgique] ; Patrick Coussement [Belgique] ; Christophe Beauloye [Belgique] ; Patrick Evrard [Belgique] ; Olivier Brasseur [Belgique] ; Frans Fierens [Belgique] ; Patrick Marechal [Belgique] ; Dan Schelfaut [Belgique] ; Vincent Floré [Belgique] ; Claude Hanet [Belgique]

Source :

RBID : pubmed:32727305

Abstract

AIMS

The current study assessed the impact of COVID-19-related public containment measures (i.e. lockdown) on the ST elevation myocardial infarction (STEMI) epidemic in Belgium.

METHODS AND RESULTS

Clinical characteristics, reperfusion therapy modalities, COVID-19 status and in-hospital mortality of consecutive STEMI patients who were admitted to Belgian hospitals for percutaneous coronary intervention (PCI) were recorded during a three-week period starting at the beginning of the lockdown period on 13 March 2020. Similar data were collected for the same time period for 2017-2019. An evaluation of air quality revealed a 32% decrease in ambient NO

CONCLUSION

The present study revealed a 26% reduction in STEMI admissions and a delay in treatment of STEMI patients. Less exposure to external STEMI triggers (such as ambient air pollution) and/or reluctance to seek medical care are possible explanations of this observation.


DOI: 10.1080/00015385.2020.1796035
PubMed: 32727305


Affiliations:


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Le document en format XML

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<name sortKey="Beauloye, Christophe" sort="Beauloye, Christophe" uniqKey="Beauloye C" first="Christophe" last="Beauloye">Christophe Beauloye</name>
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<name sortKey="Brasseur, Olivier" sort="Brasseur, Olivier" uniqKey="Brasseur O" first="Olivier" last="Brasseur">Olivier Brasseur</name>
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<nlm:affiliation>Belgian Interregional Environment Agency, Brussels, Belgium.</nlm:affiliation>
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<name sortKey="Schelfaut, Dan" sort="Schelfaut, Dan" uniqKey="Schelfaut D" first="Dan" last="Schelfaut">Dan Schelfaut</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Cardiology, OLV Aalst, Aalst, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Cardiology, OLV Aalst, Aalst</wicri:regionArea>
<wicri:noRegion>Aalst</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Flore, Vincent" sort="Flore, Vincent" uniqKey="Flore V" first="Vincent" last="Floré">Vincent Floré</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Cardiology, Hospital Maria Middelares, Ghent, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Cardiology, Hospital Maria Middelares, Ghent</wicri:regionArea>
<wicri:noRegion>Ghent</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hanet, Claude" sort="Hanet, Claude" uniqKey="Hanet C" first="Claude" last="Hanet">Claude Hanet</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Cardiology, Catholic University Hospital Mont-Godinne, Brussels, Belgium.</nlm:affiliation>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Cardiology, Catholic University Hospital Mont-Godinne, Brussels</wicri:regionArea>
<placeName>
<settlement type="city">Bruxelles</settlement>
<region nuts="2">Région de Bruxelles-Capitale</region>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Acta cardiologica</title>
<idno type="eISSN">1784-973X</idno>
<imprint>
<date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
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<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<b>AIMS</b>
</p>
<p>The current study assessed the impact of COVID-19-related public containment measures (i.e. lockdown) on the ST elevation myocardial infarction (STEMI) epidemic in Belgium.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS AND RESULTS</b>
</p>
<p>Clinical characteristics, reperfusion therapy modalities, COVID-19 status and in-hospital mortality of consecutive STEMI patients who were admitted to Belgian hospitals for percutaneous coronary intervention (PCI) were recorded during a three-week period starting at the beginning of the lockdown period on 13 March 2020. Similar data were collected for the same time period for 2017-2019. An evaluation of air quality revealed a 32% decrease in ambient NO</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>CONCLUSION</b>
</p>
<p>The present study revealed a 26% reduction in STEMI admissions and a delay in treatment of STEMI patients. Less exposure to external STEMI triggers (such as ambient air pollution) and/or reluctance to seek medical care are possible explanations of this observation.</p>
</div>
</front>
</TEI>
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<MedlineCitation Status="Publisher" Owner="NLM">
<PMID Version="1">32727305</PMID>
<DateRevised>
<Year>2020</Year>
<Month>07</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1784-973X</ISSN>
<JournalIssue CitedMedium="Internet">
<PubDate>
<Year>2020</Year>
<Month>Jul</Month>
<Day>30</Day>
</PubDate>
</JournalIssue>
<Title>Acta cardiologica</Title>
<ISOAbbreviation>Acta Cardiol</ISOAbbreviation>
</Journal>
<ArticleTitle>Impact of COVID-19-related public containment measures on the ST elevation myocardial infarction epidemic in Belgium: a nationwide, serial, cross-sectional study.</ArticleTitle>
<Pagination>
<MedlinePgn>1-7</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1080/00015385.2020.1796035</ELocationID>
<Abstract>
<AbstractText Label="AIMS" NlmCategory="OBJECTIVE">The current study assessed the impact of COVID-19-related public containment measures (i.e. lockdown) on the ST elevation myocardial infarction (STEMI) epidemic in Belgium.</AbstractText>
<AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">Clinical characteristics, reperfusion therapy modalities, COVID-19 status and in-hospital mortality of consecutive STEMI patients who were admitted to Belgian hospitals for percutaneous coronary intervention (PCI) were recorded during a three-week period starting at the beginning of the lockdown period on 13 March 2020. Similar data were collected for the same time period for 2017-2019. An evaluation of air quality revealed a 32% decrease in ambient NO
<sub>2</sub>
concentrations during lockdown (19.5 µg/m³ versus 13.2 µg/m³,
<i>p</i>
 < .001). During the three-week period, there were 188 STEMI patients admitted for PCI during the lockdown versus an average 254 STEMI patients before the lockdown period (incidence rate ratio = 0.74,
<i>p</i>
 = .001). Reperfusion strategy was predominantly primary PCI in both time periods (96% versus 95%). However, there was a significant delay in treatment during the lockdown period, with more late presentations (>12 h after onset of pain) (14% versus 7.6%,
<i>p</i>
 = .04) and with longer door-to-balloon times (median of 45 versus 39 min,
<i>p</i>
 = .02). Although the in-hospital mortality between the two periods was comparable (5.9% versus 6.7%), 5 of the 7 (71%) COVID-19-positive STEMI patients died.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The present study revealed a 26% reduction in STEMI admissions and a delay in treatment of STEMI patients. Less exposure to external STEMI triggers (such as ambient air pollution) and/or reluctance to seek medical care are possible explanations of this observation.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Claeys</LastName>
<ForeName>Marc J</ForeName>
<Initials>MJ</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-6628-9543</Identifier>
<AffiliationInfo>
<Affiliation>Department of Cardiology, University Hospital Antwerp, Antwerp, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Argacha</LastName>
<ForeName>Jean-François</ForeName>
<Initials>JF</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, University Hospital Brussels, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Collart</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Centre de recherche en Epidémiologie, Biostatistiques et Recherche Clinique, School of Public Health, Université Libre de Bruxelles, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Carlier</LastName>
<ForeName>Marc</ForeName>
<Initials>M</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, GHDC, Charleroi, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Van Caenegem</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo>
<Affiliation>Division of Cardiovascular Intensive Care, Cliniques universitaires Saint Luc, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Sinnaeve</LastName>
<ForeName>Peter R</ForeName>
<Initials>PR</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0003-4716-5892</Identifier>
<AffiliationInfo>
<Affiliation>Department of Cardiology, University Hospital Leuven, Leuven, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Desmet</LastName>
<ForeName>Walter</ForeName>
<Initials>W</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, University Hospital Leuven, Leuven, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dubois</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, CHU, Charleroi, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Stammen</LastName>
<ForeName>Francis</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, Hospital Roeselare, Roeselare, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Gevaert</LastName>
<ForeName>Sofie</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, Ghent University Hospital, Ghent, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Pourbaix</LastName>
<ForeName>Suzanne</ForeName>
<Initials>S</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, CHR Citadelle Liège, Liège, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Coussement</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, Hospital Sint-Jan Brugge, Brugge, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Beauloye</LastName>
<ForeName>Christophe</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Division of Cardiology and Pole of Cardiovascular Research, Institut de Recherche Experimentale et Clinique, Cliniques universitaires Saint Luc, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Evrard</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Intensive Care, Belgium Catholic University Hospital Mont-Godinne, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Brasseur</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo>
<Affiliation>Laboratory of Environmental Research, Brussels Environment, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Fierens</LastName>
<ForeName>Frans</ForeName>
<Initials>F</Initials>
<AffiliationInfo>
<Affiliation>Belgian Interregional Environment Agency, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Marechal</LastName>
<ForeName>Patrick</ForeName>
<Initials>P</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, University hospital of Liege, Liège, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Schelfaut</LastName>
<ForeName>Dan</ForeName>
<Initials>D</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, OLV Aalst, Aalst, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Floré</LastName>
<ForeName>Vincent</ForeName>
<Initials>V</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, Hospital Maria Middelares, Ghent, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Hanet</LastName>
<ForeName>Claude</ForeName>
<Initials>C</Initials>
<AffiliationInfo>
<Affiliation>Department of Cardiology, Catholic University Hospital Mont-Godinne, Brussels, Belgium.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
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<Year>2020</Year>
<Month>07</Month>
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</ArticleDate>
</Article>
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<Country>England</Country>
<MedlineTA>Acta Cardiol</MedlineTA>
<NlmUniqueID>0370570</NlmUniqueID>
<ISSNLinking>0001-5385</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">PCI</Keyword>
<Keyword MajorTopicYN="N">STEMI</Keyword>
<Keyword MajorTopicYN="N">containment</Keyword>
<Keyword MajorTopicYN="N">mortality</Keyword>
<Keyword MajorTopicYN="N">pollution</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="entrez">
<Year>2020</Year>
<Month>7</Month>
<Day>31</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed">
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<Month>7</Month>
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</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2020</Year>
<Month>7</Month>
<Day>31</Day>
<Hour>6</Hour>
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<ArticleIdList>
<ArticleId IdType="pubmed">32727305</ArticleId>
<ArticleId IdType="doi">10.1080/00015385.2020.1796035</ArticleId>
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</pubmed>
<affiliations>
<list>
<country>
<li>Belgique</li>
</country>
<region>
<li>Région de Bruxelles-Capitale</li>
</region>
<settlement>
<li>Bruxelles</li>
</settlement>
<orgName>
<li>Université libre de Bruxelles</li>
</orgName>
</list>
<tree>
<country name="Belgique">
<noRegion>
<name sortKey="Claeys, Marc J" sort="Claeys, Marc J" uniqKey="Claeys M" first="Marc J" last="Claeys">Marc J. Claeys</name>
</noRegion>
<name sortKey="Argacha, Jean Francois" sort="Argacha, Jean Francois" uniqKey="Argacha J" first="Jean-François" last="Argacha">Jean-François Argacha</name>
<name sortKey="Beauloye, Christophe" sort="Beauloye, Christophe" uniqKey="Beauloye C" first="Christophe" last="Beauloye">Christophe Beauloye</name>
<name sortKey="Brasseur, Olivier" sort="Brasseur, Olivier" uniqKey="Brasseur O" first="Olivier" last="Brasseur">Olivier Brasseur</name>
<name sortKey="Carlier, Marc" sort="Carlier, Marc" uniqKey="Carlier M" first="Marc" last="Carlier">Marc Carlier</name>
<name sortKey="Collart, Philippe" sort="Collart, Philippe" uniqKey="Collart P" first="Philippe" last="Collart">Philippe Collart</name>
<name sortKey="Coussement, Patrick" sort="Coussement, Patrick" uniqKey="Coussement P" first="Patrick" last="Coussement">Patrick Coussement</name>
<name sortKey="Desmet, Walter" sort="Desmet, Walter" uniqKey="Desmet W" first="Walter" last="Desmet">Walter Desmet</name>
<name sortKey="Dubois, Philippe" sort="Dubois, Philippe" uniqKey="Dubois P" first="Philippe" last="Dubois">Philippe Dubois</name>
<name sortKey="Evrard, Patrick" sort="Evrard, Patrick" uniqKey="Evrard P" first="Patrick" last="Evrard">Patrick Evrard</name>
<name sortKey="Fierens, Frans" sort="Fierens, Frans" uniqKey="Fierens F" first="Frans" last="Fierens">Frans Fierens</name>
<name sortKey="Flore, Vincent" sort="Flore, Vincent" uniqKey="Flore V" first="Vincent" last="Floré">Vincent Floré</name>
<name sortKey="Gevaert, Sofie" sort="Gevaert, Sofie" uniqKey="Gevaert S" first="Sofie" last="Gevaert">Sofie Gevaert</name>
<name sortKey="Hanet, Claude" sort="Hanet, Claude" uniqKey="Hanet C" first="Claude" last="Hanet">Claude Hanet</name>
<name sortKey="Marechal, Patrick" sort="Marechal, Patrick" uniqKey="Marechal P" first="Patrick" last="Marechal">Patrick Marechal</name>
<name sortKey="Pourbaix, Suzanne" sort="Pourbaix, Suzanne" uniqKey="Pourbaix S" first="Suzanne" last="Pourbaix">Suzanne Pourbaix</name>
<name sortKey="Schelfaut, Dan" sort="Schelfaut, Dan" uniqKey="Schelfaut D" first="Dan" last="Schelfaut">Dan Schelfaut</name>
<name sortKey="Sinnaeve, Peter R" sort="Sinnaeve, Peter R" uniqKey="Sinnaeve P" first="Peter R" last="Sinnaeve">Peter R. Sinnaeve</name>
<name sortKey="Stammen, Francis" sort="Stammen, Francis" uniqKey="Stammen F" first="Francis" last="Stammen">Francis Stammen</name>
<name sortKey="Van Caenegem, Olivier" sort="Van Caenegem, Olivier" uniqKey="Van Caenegem O" first="Olivier" last="Van Caenegem">Olivier Van Caenegem</name>
</country>
</tree>
</affiliations>
</record>

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